PubMed journal article [Idiopathic pulmonary hemosiderosis were found in PRIME PubMed. Download Source. Revista chilena de pediatría pg PubMed journal article [Idiopathic pulmonary hemosiderosis: review of literature and case report were found in La Pediatria Sep 30 pg Revista Cubana de Pediatría Idiopathic pulmonary hemosiderosis is those processes characterized by anomalous depots of hemosiderin in the pulmonary.

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He was initiated on corticosteroid therapy, later associated to an immunosuppressive agent, with subsequent correction of anemia and of the pediatroa pattern. Long-term prednisone and azathioprine treatment of a patient with idiopathic pulmonary hemosiderosis. Pulmonary hemosiderosis PH is a rare disease that may hejosiderosis at any age, although it generally affects children, with an estimated incidence of 0.

As there was a poor response to intravenous iron therapy, he was readmitted to further investigate gastrointestinal bleeding. Received Apr 1; Accepted Sep Open in a separate window.

Idiopathic pulmonary hemosiderosis hemlsiderosis adults: To confirm alveolar hemorrhage, a fibrobronchoscopy was performed. There are several known causes of diffuse alveolar hemorrhage vasculitides, connective tissue disorders, Heiner’s syndrome, cardiovascular diseases, among others.

Severe iron-deficiency anemia as initial manifestation of pulmonary hemosiderosis in a child

The low pressure and high capacitance of the pulmonary circulation result in chronic, diffuse and low-grade hemorrhage. Idiopathic pulmonary hemosiderosis in pedixtria 9-year-old girl. After 6 days, he was discharged on oral iron therapy, with Hb of 8.

Annals of Pediatrics is the Body of Scientific Expression of the Association and is the vehicle through which members communicate. After starting steroid treatment there was a progressive increase in Hb level and improvement of radiological hemosiderosiw.

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He was transfused with packed red blood cells and was admitted for treatment and investigation. Upper and lower hemosideerosis endoscopies with biopsies were performed and no hemorrhagic lesion was found, and the mucosa was macroscopically and histologically normal.

SRJ is a prestige metric based on the idea that not all citations are the same. He had microcytic and hypochromic anemia refractory to iron therapy. Diffuse bilateral opacity with ill-defined edges, with a predominantly central location. Hemosideeosis the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License.

Treatment of idiopathic pulmonary hemosiderosis with inhaled flunisolide. After 3 days, he maintained fever and the chest radiograph showed a diffuse bilateral opacity with ill-defined edges, interpreted as an atypical pneumonia, and he was started on clarithromycin. Orphanet J Rare Dis.

pediqtria Five days after being discharged, he was seen again for fever, asthenia, coryza, and productive cough. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

[Hydroxychloroquine in pediatric idiopathic pulmonary hemosiderosis–a case report].

Vitamin B 12 and folic acid were within normal range and the bone peidatria smear was compatible with sideropenia. J Pediatr Rio J. For this reason, he was not submitted to an upper esophagogastroduodenoscospy, as previously planned. The prognosis of idiopathic PH tends to improve with age and is more favorable when the diagnosis is made before the progression to pulmonary fibrosis. The cytological exam of the bronchoalveolar lavage showed hemosiderin-laden macrophages.


Severe respiratory distress in a child with pulmonary idiopathic hemosiderosis initially presenting with iron-deficiency anemia. Foi iniciado tratamento com oxacilina e azitromicina. Analytically he had Hb of 2. Services on Demand Journal. After the etiological study, the diagnosis of idiopathic pulmonary hemosiderosis was made by exclusion.

In this situation, therapy is often started at the stage in which pulmonary fibrosis has already developed, with a higher risk of complications and worse prognosis.

Anemia might be the only hemosidedosis of PH, preceding any other symptom and sign by several months.

Idiopathic pulmonary hemosiderosis

This case highlights the importance of including chest radiography in the investigation of blood loss of unknown origin. Support Center Support Center. J Clin Case Rep. The gold standard for the diagnosis of diffuse alveolar hemorrhage is pulmonary biopsy, which may also enable the diagnosis of some of the specific causes of hemorrhage.

He had no macroscopic blood loss, either from gastrointestinal or urinary tract. Diffuse alveolar hemorrhage is caused by loss of integrity of the basement membrane of pulmonary capillaries, with consequent leakage of blood into the alveolar space. Iron-deficiency anemia is the most frequent hematologic disease in pediatrics.

A favorable prognosis may be expected in our case, as there were no major episodes of hemorrhage and response to therapy was favorable.

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